These facts are unimportant in ________, but ...

These facts are unimportant in ________, but if you put them together, you may find something unusual.

A．it                B．them             C．itself             D．themselves

高三英语单项填空简单题查看答案及解析

—Put these glasses away before they　　　　　　 ．

—OK．I'll put them in the cupboard．

A．have broken　　     B．are breaking　　　　         C．will be broken         D．get broken

高三英语单项填空中等难度题查看答案及解析

— Put these glasses away before they______.

— OK, I’ll put them in the cupboard.

A. have broken      B. are breaking         C. get broken      D. will be broken

高三英语单项填空困难题查看答案及解析

“ New and improved. ” These words are put in so many marketing campaigns that we tend to accept them as linked. But many new drugs aren't an improvement over the best existing drug for a given condition, and the fast drug-approval processes in recent years have added to the uncertainty about their advantages.

A recent report in the British Medical Journal, "New Drugs: Where Did We Go Wrong and What Can We Do Better?, analysed the issue, The authors looked at 216 drugs approved between 2011 and 2017 ； 152 were newly developed, and 64 were existing medicine approved for new uses. Only 25% offered a major advantage over the established treatment, and fully 58% had no confirmed added benefit to reduce symptoms or improve health-related quality of life.

"This doesn’t mean there's no added benefit," lead author Wieseler said. “It just means we have no positive proof. Either we have no studies or have studies not good enough. ” Wieseler and her co-authors work for a German institute which evaluates new treatments and advises on whether the country's health care system should pay a premium ( 占)for them. Such organizations , known as health technology assessment ( HTA) agencies, work a little differently in the US, says Sean Tunis，a researcher in Baltimore: “ If payers think a new drug isn't better than an existing drug，these agencies will require .that hospitals try the cheaper drug first. ”

Germany's HTA demands trials to prove that a new treatment beats the existing standard. This isn't always practical For one thing, such studies can be expensive and time-consuming, with no guarantee of success. Secondly, it can discourage companies from attempting to develop new alternatives. This is already happening. Drug developers are increasingly focused on areas where there are no good treatments to compete with, such as rare diseases.

This lack of meaningful data to guide patients is a major point of Wieseler's paper- With accelerated approval, there are more products approved, with a greater amount of uncertainty about risks and benefits. But there are other solutions besides drug trials. One idea is to require postmarket studies to track the effectiveness of newly approved drugs—a step too often neglected.

1.What message does the recent report convey?

A.Many new drugs have no improved advantages.

B.The approval processes for new drugs are too fast.

C.Improved drugs have advantages over old ones.

D.Before 2017 no improvement was made to drugs.

2.What will US HTA agencies do when no advantage is found in new drugs?

A.Remove government premium on them.

B.Get hospitals to use the cheaper drugs.

C.Arrange financial support for the patients.

D.Put new drugs on further trials and studies.

3.What's the disadvantage of Germany's HTA trial demands?

A.Making drug companies think of illegal ways to cut cost.

B.Pushing companies to try alternatives for existing drugs.

C.Getting patients to depend on the government for support.

D.Holding companies back from improving existing drugs.

4.What is the best title for the text?

A.The Advantage of Existing Drugs

B.Misunderstanding of New and Old Drugs

C.A Dilemma with New Drug Alternatives

D.Peopled Preference for New or Old Drugs

高三英语阅读理解中等难度题查看答案及解析

＂New and improved."These words are put in so many marketing campaigns that we tend to accept them as linked.But many new drugs aren't an improvement over the best existing drug for a given condition,and the fast drug-approval processes in recent years have added to the uncertainty about their advantages.

A recent report in the British Medical Journal,"New Drugs;Where Did We Go Wrong and What We Do Better?" analyzed the issue,The authors looked at 216 drugs approved between 2011 and 2017; 152 were newly developed,and 64 were existing medicine approved for new uses. Only 25% offered a major advantage over the established treatment,and fully 58% had no confirmed added benefit to reduce symptoms or improve health-related quality of life.

＂This doesn't mean there's no added benefit,"lead author Wieseler said."It just means we have no positive proof Either we have no studies or have studies not good enough.”Wieseler and her co-authors work for a German agency which evaluates new treatments and advises on whether the country's health care system should pay a premium(补贴）for them.If payers think a new drug isn't better than an existing drug,these agencies will require that hospitals try the cheaper drug first.

Germany's HTA demands trials to prove that a new treatment beats the existing standard. This isn't always practical. For one thing, such studies can be expensive and time-consuming,with no guarantee of success.Secondly,it can discourage companies from attempting to develop new alternatives.This is already happening.Drug developers are increasingly focused on areas where there are no good treatments to compete with,such as rare diseases.

This lack of meaningful data to guide patients is a major point of Wieseler's paper.With accelerated approval,there are more products approved,with a greater amount of uncertainty about risks and benefits. But there are other solutions besides drug trials.One idea is to require postmarket studies to track the effectiveness of newly approved drugs-a step too often neglected.

1.What message does the recent report convey?

A.Improved drugs have advantages over old ones.

B.The approval processes for new drugs are too fast.

C.Many new drugs have no improved advantages.

D.Almost half the drugs approved target the special cases.

2.What's the disadvantage of Germany's HTA trial demands?

A.Making drug companies think of illegal ways to cut cost.

B.Holding companies back from improving existing drugs.

C.Getting patients to depend on the government for support.

D.Pushing companies to try alternatives for existing drugs.

3.What is the best title for the text?

A.The Advantage of Existing Drugs B.The Great Potential of New Drugs

C.People's Preference for New or Old Drugs D.A Dilemma with New Drug Alternatives

高三英语阅读理解中等难度题查看答案及解析

“New and improved. “These words are put in so many marketing campaigns that we tend to accept them as linked. But many new drugs aren’t an improvement over the best existing drug for a given condition, and the fast drug-approval processes in recent years have added to the uncertainty about their advantages.

A recent report in the British Medical Journal, “New Drugs: Where Did We Go Wrong and What Can We Do Better? “Analyzed the issue. The authors looked at 216 drugs approved between 2011 and 2017:152 were newly developed, and 64 were existing medicine approved for new uses. Only 25%offered a major advantage over the established treatment, and fully 58%had no confirmed added benefit to reduce symptoms or improve health-related quality of life.

“This doesn’t mean there’s no added benefit, “lead author Wissler said. “It just means we have no positive proof. Either we have no studies or have studies not good enough. “Wissler and her co-authors work for a German institute which evaluates new treatments and advises on whether the country’s health care system should pay a premium(补贴)for them. Such organizations, known as health technology assessment(HTA)agencies, work a little differently in the US, says Sean Tunisia researcher in Baltimore: “If payers think a new drug isn’t better than an existing drug, these agencies will require that hospitals try the cheaper drug first.”

Germanys HTA demands trials to prove that a new treatment beats the existing standard. This isn’t always practical. For one thing, such studies can be expensive and time-consuming, with no guarantee of success. Secondly, it can discourage companies from attempting to develop new alternatives. This is already happening. Drug developers are increasingly focused on areas where there are no good treatments to compete with, such as rare diseases.

This lack of meaningful data to guide patients is a major point of Wissler’s paper. With accelerated approval, there are more products approved, with a greater amount of uncertainty about risks and benefits. But there are other solutions besides drug trials. One idea is to require postmarked studies to track the effectiveness of newly approved drugs—a step too often neglected.

1.What message does the recent report convey?

A.Improved drugs have advantages over old ones.

B.Many new drugs have no improved advantages.

C.Before 2017 no improvement was made to drugs.

D.The approval processes for new drugs are too fast.

2.What will US HTA agencies do when no advantage is found in new drugs?

A.Get hospitals to use the cheaper drugs.

B.Remove government premium on them.

C.Arrange financial support for the patients.

D.Put new drugs on further trials and studies.

3.What’s the disadvantage of Germany’s HTA trial demands?

A.Getting patients to depend on the government for support.

B.Making drug companies think of illegal ways to cut cost.

C.Holding companies back from improving existing drugs.

D.Pushing companies to try alternatives for existing drugs.

4.What is the best title for the text?

A.The Advantage of Existing Drugs

B.A Dilemma with New Drug Alternatives

C.Misunderstanding of New and Old Drugs

D.People’s Preference for New or Old Drug

高三英语阅读理解困难题查看答案及解析

If you are in any doubt as to _____ you should be doing these exercises, consult your doctor.

高三英语单项填空中等难度题查看答案及解析

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1.Which of the following books save you the most?

A. Furiously Happy

B. Make Your Bed

C. The Silent Wife

D. Magpie Murders

2.Which of the following books can be ordered in advance?

A. The Silent Wife

B. Make Your Bed

C. Furiously Happy

D. Magpie Murders

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A. They are all best sellers of the same year.

B. They all have hardcover and paperback.

C. They are all mystery stories.

D. They all have discounted prices.

高三英语阅读理解中等难度题查看答案及解析

If you are heading for Paris this year， be sure to include at least one of these shopping malls in your schedule．

Au Printemps

Tel： 01133014282

Located near the Paris Opera， this huge store is well-known for household goods as well as its fashion． The tore also offers many services to overseas visitors， including shipping， translation and a personal shopping service． Au Printemps， whose name means springtime， hosts several free fashion shows each week． The store's beauty department has one of the world's largest selections of perfumes．

Galeries Lafayatte

Tel： 01133014283

The Galeries Lafayette was built in 1906． It is as much fun to look at as it is to shop in this 10-storey shopping palace． In fact， the flagship store is the second most visited attraction in Paris． After the Louvre Museum． This shopping palace specializes in women's clothing． Make sure to take in the view from the tea shop on the top floor； it's well worth the visit．

Le Bon Marche

Tel： 01133014439

This stylish Left Bank department store was Paris' first such store． Designed by Gustave Eiffel， Le Bon Marche is particularly known for its food hall， its wedding shops and its selection of modern clothes．

La Forum des Halles

Tel： 01133014476

This modern， underground shopping center was built in 1979． La Forum des Halles， the three-storey-tall shopping center offers everything from souvenirs to haute couture（高级女子时装）to entertainment， such as first-run movies and street performers． The shopping center is attached to the busy La Halle-Chatelet metro station and can be easily reached from all over Paris．

1.Which of the following places attracts the most visitors according to the passage？ ______

A. The Louvre Museum． B. The Paris Opera．

C. La Forum des Halles． D. Au Printemps．

2.Which of the stores pays its special attention to women's dressing？ ______

A. Le Bon Marche． B. Galeries Lafayette．

C. La Forum des Halles． D. Au Printemps．

3.We can learn from the passage that ______ ．

A. Au Printemps is famous for its food hall．

B. La Forum des Halles is next to the metro station．

C. the clothes in Le Bin Marche are usually very cheap．

D. the tea shop that is worth visiting is on the ninth floor of Galeries Lafayette．

高三英语阅读理解简单题查看答案及解析

If you are heading for Paris this year, be sure to include at least one of these shopping malls in your schedule.

Au Printemps

Tel: 01133014282

Located near the Paris Opera, this huge store is well-known for household goods as well as its fashion. The store also offers many services to overseas visitors, including shipping, translation and a personal shopping service. Au Printemps, whose name means springtime, hosts several free fashion shows each week. The store’s beauty department has one of the world’s largest selections of perfumes.

Galeries Lafayette

Tel: 01133014283

The Galeries Lafayette was built in 1906. It is as much fun to look at as it is to shop in this 10-storey shopping palace. In fact, the flagship store is the second most visited attraction in Paris, after the Louvre Museum. This shopping palace specializes in women’s clothing. Make sure to take in the view from the tea shop on the top floor; it’s well worth the visit.

Le Bon Marche

Tel: 01133014439

This stylish Left Bank department store was Paris’ first such store. Designed by Gustave Eiffel, Le Bon Marche is particularly known for its food hall, its wedding shops and its selection of modern clothes.

La Forum des Halles

Tel: 01133014476

This modern, underground shopping center was built in 1979. La Forum des Halles, the three-storey-tall shopping center offers everything from souvenirs to haute couture（高级女子时装）to entertainment, such as first-run movies and street performers. The shopping center is attached to the busy La Halle-Chatelet metro station and can be easily reached from all over Paris.

1.Which of the following places attracts the most visitors according to the passage?

A. The Louvre Museum.

B. The Paris Opera.

C. La Forum des Halles.

D. Au Printemps.

2.Which of the stores pays its special attention to women’s dressing?

A. Le Bon Marche.

B. Au Printemps.

C. La Forum des Halles.

D. Galeries Lafayette.

3.We can learn from the passage that 　　　　　　　　　　　　　　　　　　　　　　　　 .

A. Au Printemps is famous for its food hall

B. La Forum des Halles is next to the metro station

C. the clothes in Le Bon Marche are usually very cheap

D. the tea shop that is worth visiting is on the ninth floor of Galeries Lafayette

高三英语阅读理解简单题查看答案及解析