The explorer got a disease in blood for the _...

The explorer got a disease in blood for the _______ of fresh vegetables and fruit.

A. sake     B. lack      C. ignorance      D. benefit

高三英语单项填空中等难度题查看答案及解析

The invention of artificial hearts marked a turning point in the battle      heart disease．

A．among        B．for      C．against     D．between

高三英语单项填空中等难度题查看答案及解析

Authorities in China have approved a drug for the treatment of Alzheimer’s disease (早老性痴呆), the first new medicine with the potential to treat the cognitive (认知的) disorder in 17 years.

The seaweed-based drug, called Oligomannate, can be used for the treatment of mild to moderate Alzheimer’s, according to a statement from China’s drug safety agency. The approval is conditional however, meaning that while it can go on sale during additional clinical trials, it will be strictly monitored and could be withdrawn if any safety issues should arise.

In September, the team behind the new drug, led by Geng Meiyu at the Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, said they were inspired to look into seaweed due to the relatively low incidence of Alzheimer’s among people who consume it regularly.

In a paper in the journal Cell Research, Geng’s team described how a sugar contained within seaweed prevents certain bacteria contained in the gut (肠子) which can cause neural decline and infection of the brain, leading to Alzheimer’s.

This mechanism was confirmed during a clinical trial carried out by Green Valley, a Shanghai based pharmaceutical company that will be bringing the new drug to market.

Conducted on 818 patients, the trial found that Oligomannate-which is got from brown algae (海藻)－can statistically improve cognitive function among people with Alzheimer’s in as little as four weeks, according to a statement from Green Valley.

The company said Oligomannate will be available in China “very soon”, and it is currently seeking approval to market it abroad, with plans to launch third-phase clinical trials in the US and Europe in early 2020.

1.What can Oligomannate be used for?

A.Curing the severe Alzheimer’s.

B.Treating the minor Alzheimer’s.

C.Killing all bacteria in the body.

D.Treating all cognitive disorders.

2.What inspired the team to look into the seaweed?

A.The praise from a patient with Alzheimer’s.

B.An incident of brain infection in the laboratory.

C.The approval for the seaweed research from the authorities.

D.The low occurrence of the disease among people eating the seaweed.

3.What causes the Alzheimer’s?

A.The brown algae.

B.The wound of the head.

C.Some bacteria contained in the gut.

D.A sugar contained within seaweed.

4.What is the company Green Valley’s attitude to the future of Oligomannate?

A.Optimistic. B.Uncertain.

C.Indifferent. D.Anxious.

高三英语阅读理解中等难度题查看答案及解析

AIDS may be one of the most undesirable diseases in the world. Luckily, there is now hope for AIDS patients.

According to a recent paper published in the New England Journal of Medicine，Chinese scientists have successfully used CRISPR technology -a method of gene editing-to treat a patient with HIV. While it may not have cured the patient fully, it still represents a huge step forward in fighting the disease.

The patient was a 27-year-old Chinese man who was diagnosed with both AIDS and acute lymphoblastic leukemia (淋巴母细胞白血病), a type of blood cancer. Despite his bleak situation, doctors offered him a little hope: a bone marrow (骨髓) transplant to treat his cancer and an experimental treatment for his HIV. They used this chance to edit the DNA in bone marrow stem cells (干细胞) from a donor before transplanting the cells into the patient.

Specifically, the treatment involved using the gene-editing tool CRISPR-Cas9 to delete a gene known as CCR5, which encodes (给…编码) a protein that HIV uses to get inside human cells. Without the gene, HIV is unable to enter cells. Talking about the gene, lead scientist Deng Hongkui told CNN, “After being edited, the cells and the blood cells they produce have the ability to resist HIV infection.” Nineteen months after the treatment, the patients leukemia was in complete remission( 缓 解 ) and donor cells without CCR5 remained, according to the research paper.

Though the transplant didn't cure the man’s HIV, it still showed the effectiveness of gene-editing technology, as there was no indication of any unintended genetic changes-a major concern with past gene-editing treatment experiments. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security in the United States, who was not involved in the study, praised the treatment. “They did a very creative experiment, and it was safe,” he told Live Science. “It should be viewed as a success.”

Deng believes gene-editing technology could “bring a new dawn” to blood related diseases such as AIDS and sickle-cell anaemia ( 镰 状 细 胞 贫 血 ). “Thanks to this new technology, the goal of a functional cure for AIDS is getting closer and closer,” he said.

1.The underlined word “bleak” in Paragraph3 probably means “______”.

A.hopeless

B.unstable

C.embarrassing

D.unique

2.How did the treatment fight against HIV?

A.By identifying and killing HIV.

B.By changing the structure of HIV.

C.By preventing HIV entering cells.

D.By removing a protein HIV feeds on.

3.What is the result of the treatment?

A.Gene-edited cells are able to resist HIV infection.

B.The number of cells infected by HIV has decreased.

C.CCR5 and other genes in the patient's cells are changed.

D.Unintended genetic changes have taken place in the patient's cells.

4.What can we know about the experiment?

A.It pointed out the problems of gene treatment.

B.It provided a new way to cure AIDS patients fully.

C.It could offer a safe treatment for blood-related diseases.

D.It was the first example to use gene-editing tool to treat AIDS.

高三英语阅读理解困难题查看答案及解析

AIDS may be one of the most undesirable diseases in the world. Luckily, there is now hope for AIDS patients. According to a recent paper published in the New England Journal of Medicine, Chinese scientists have successfully used CRISPR technology-a method of gene editing-to treat a patient with HIV. While it may not have cured the patient fully, it still represents a huge step forward in fighting the disease.

The patient was a 27-year-old Chinese man who was diagnosed with both AIDS and acute lymphoblastic leukemia, a type of blood cancer. Despite his bleak situation, doctors offered him a glimmer of hope: a bone marrow (骨髓) transplant to treat his cancer and an experimental treatment for his HIV.

They edited the DNA in bone marrow stem cells from a donor before transplanting the cells into the patient. Specifically, the treatment involved using the gene-editing tool CRISPR-Cas9 to delete a gene known as CCRS, which encodes a protein that HIV uses to get inside human cells. Without the gene, HIV is unable to enter cells. Talking about the gene, lead scientist Deng Hongkui told CNN, “After being edited, the cells-and the blood cells they produce-have the ability to resist HIV infection.” Nineteen months after the treatment, the patient’s leukemia was in complete relief and donor cells without CCR5 remained, according to the research paper.

Though the transplant did not cure the man’s HIV, it still showed the effectiveness of gene-editing technology, as there was no indication of any unintended genetic alterations (改变) -a major concern with past gene therapy experiments.

Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security in the United States, who was not involved in the study, praised the treatment. “They did a very innovative experiment, it was safe,” he told Live Science. “It should be viewed as a success.”

Deng believes gene-editing technology could “bring a new dawn” to blood-related diseases such as AIDS and sickle cell anemia. Thanks to this new technology, “the goal of a functional cure for AIDS is getting closer and closer,” he said.

1.How did the new treatment fight against HIV?

A.By preventing HIV from entering cells. B.By changing the structure of HIV.

C.By removing a protein that HIV feeds on. D.By identifying and killing HIV.

2.What was the result of the treatment?

A.CCR5 and other genes in the patient’s cells were changed.

B.Some of the patient’s blood cells could resist HIV infection.

C.HIV could no longer get into the patient’s cells.

D.The donor cells without CCR5 disappeared finally.

3.What do we know about the experiment?

A.It has provided an innovative way to cure AIDS patients.

B.It pointed out the problems of gene therapy for AIDS.

C.It’s the first experiment to use gene-editing technology to treat AIDS.

D.It could offer a safe treatment for blood-related diseases.

高三英语阅读理解中等难度题查看答案及解析

After having worked in the University of Maryland for three years, I got a job offer from another university---Lynn University. I left my letter of offer on my present boss's desk, turned around, and closed the door quietly. I was expecting a call from my boss saying congratulations, which would show her approval of my leaving.

In the afternoon, my boss called me, saying, "Can we meet tomorrow? "That was a good signal. The next day, I met with my boss. She said, 'Nicholas, we want you. What do you want?" I said, "Boss, I deserve a significant pay raise this year due to my outstanding performance. I think I need a 10% pay raise next year as a condition for me to stay here." My boss said, "No problem.''

When I left her office, I called Lynn University and told them that I was going to get a 10% pay raise. They had to give me 10% more than their original pay offer in order for me to accept the job. The new boss told me that he was willing to give me more, but I would feel very bad working at this university with such a high pay. I would win a battle, but I would lose a war. He said, "The problem is that your colleague will earn less than you, so you will feel guilty(内疚)and uncomfortable. But, I can still give you 5% more than the original offer."

I delivered this massage to my present boss, and she told me that she would give me another 5% pay raise if I promised to refuse this new job offer. On top of that, she would strongly support my early promotion（晋升)from assistant professor to associate professor. According to the university policy, you must take at least 6 years to get promoted. That was my third year of employment at this university. After refusing the new job offer, I finally enjoyed both a pay raise and early promotion.

1.In paragraph 2, what does Nicholas mean by "That was a good signal"?

A. His boss would approve his leaving the University of Maryland.

B. He would leave his present job and work for Lynn University.

C. His boss would talk with him about a possible pay offer.

D. His friends would congratulate him on getting a new job offer.

2.Why did the new boss agree to another 5% raise when Nicholas asked for 10% the next day?

A .He did not have the right to make such a big pay offer.

B. he did not want Nicholas to earn more than he did.

C. Nicholas was not experienced enough to get such a raise.

D. Nicholas would not feel good for earning too much more than others.

3.How much pay raise did the author finally get as a result of refusing the new job offer?

A. 5%　　　　　 B. 10%　　　　 C. 15%　　　　　 D. 20%

4.In the text, the author mainly tells his experience of________.

A. earning a pay raise

B. refusing a job offer

C. applying for a new position

D. making decisions in the workplace

高三英语阅读理解中等难度题查看答案及解析

After having worked in the University of Maryland for three years, I got a job offer from another university---Lynn University. I left my letter of offer on my present boss's desk, turned around, and closed the door quietly. I was expecting a call from my boss saying congratulations, which would show her approval of my leaving.

In the afternoon, my boss called me, saying, "Can we meet tomorrow? "That was a good signal. The next day, I met with my boss. She said, 'Nicholas, we want you. What do you want?" I said, "Boss, I deserve a significant pay raise this year due to my outstanding performance. I think I need a 10% pay raise next year as a condition for me to stay here." My boss said, "No problem.''

When I left her office, I called Lynn University and told them that I was going to get a 10% pay raise. They had to give me 10% more than their original pay offer in order for me to accept the job. The new boss told me that he was willing to give me more, but I would feel very bad working at this university with such a high pay. I would win a battle, but I would lose a war. He said, "The problem is that your colleague will earn less than you, so you will feel guilty(内疚)and uncomfortable. But, I can still give you 5% more than the original offer."

I delivered this massage to my present boss, and she told me that she would give me another 5% pay raise if I promised to refuse this new job offer. On top of that, she would strongly support my early promotion（晋升)from assistant professor to associate professor. According to the university policy, you must take at least 6 years to get promoted. That was my third year of employment at this university. After refusing the new job offer, I finally enjoyed both a pay raise and early promotion.

1.In paragraph 2, what does Nicholas mean by "That was a good signal"?

A. His boss would approve his leaving the University of Maryland.

B. He would leave his present job and work for Lynn University.

C. His boss would talk with him about a possible pay offer.

D. His friends would congratulate him on getting a new job offer.

2.Why did the new boss agree to another 5% raise when Nicholas asked for 10% the next day?

A .He did not have the right to make such a big pay offer.

B. he did not want Nicholas to earn more than he did.

C. Nicholas was not experienced enough to get such a raise.

D. Nicholas would not feel good for earning too much more than others.

3.How much pay raise did the author finally get as a result of refusing the new job offer?

A. 5%　　　　 B. 10%　　　 C. 15%　　　 D. 20%

4.In the text, the author mainly tells his experience of________.

A. earning a pay raise

B. refusing a job offer

C. applying for a new position

D. making decisions in the workplace

高三英语阅读理解中等难度题查看答案及解析

He got to the station early,__________ missing his train.

A. in case of      B. instead of         C. for fear of         D. in search of

高三英语单项填空中等难度题查看答案及解析

To Whom It May Concern:

My husband and I got married in 1965 and for the first ten years of our marriage I was very happy to stay home and raise our three children. Then four years ago, our youngest child went to school and I thought I might go back to work.

My husband was very supportive and helped me to make my decision. He emphasized all of the things I can do around the house, and said he thought I could be a great success in business.

After several weeks of job-hunting I found my present job, which is working for a small public relations firm. At first, my husband was very proud of me and would tell his friends , "My clever little wife can run that company she's working for."

But as his joking remark approached reality, my husband stopped talking to me about my job. I have received several promotions and pay increases, and I am now making more money than he is. I can buy my own clothes and a new car. Because of our combined incomes, my husband and I can do many things that we had always dreamed of doing, but we don't do these things because he is very unhappy.

We fight about little things and my husband is very critical of me in front of our friends. For the first time in our marriage, I think there is a possibility that our marriage may come to an end.

I love my husband very much, and I don't want him to feel inferior（自惭形秽）, but I also love my job. I think I can be a good wife and a working woman, but I don't know how. Can you give me some advice? Will I have to choose one or the other or can I keep both my husband and my new career?

Please help. "Distressed"

45.The letter was most probably written ________.

A. in 1975                   B. around 1980     C. four years ago     D. in 1965

46. Her husband ________ when she first found her present job.

A. was very critical of her           B. felt disappointed

C. was proud of her                     D. was happy but critical

47. What does the underlined word "promotion" mean?

A. scolding              B. criticism        C. prize          D. advancement

48. As her income increased, ________.

A. she found a gap（分歧）emerged（显露）between her and her husband

B. she bought more clothes and a house

C. she did the many things she and her husband dreamed of

D. she felt very proud of herself

高三英语阅读理解简单题查看答案及解析

—He got the first prize in a National Contest of Popular Music.

—Oh. That’s what he _____ for years.

A. had been expecting   B. has expected     C. expected           D. has been expecting

高三英语单项填空简单题查看答案及解析